If I use Smeargle's "Portrait" Poke-POWER and find "Engineer's Adjustments" in my opponent's hand, do I have to use it if I have an Energy card in my hand?
Yes, if you have an energy card and you choose Engineer's Adjustments, you have to discard the energy and draw 4 cards.
Source: PUI Rules Team (2010-12-09), PUI Rules Team (2011-03-17)
What happens if I use Smeargle's "Portrait" Poke-POWER, but I cannot satisfy the conditions of any of my opponent's Supporters?
You get to look at the opponent's hand, and that's all.
Source: PUI Rules Team (2010-12-09)
When using Smeargle's "Portrait" Poke-POWER, can I choose a Supporter that will have no effect?
You cannot pick a supporter you couldn't normally use; for example you can't choose "Twins" unless you are behind on prizes at that time, nor Aaron's Collection if you don't have anything in your Discard Pile. You would have to choose a different Supporter if one is available.
Source: PUI Rules Team (2010-12-09)
Can I use Smeargle's "Portrait" Poke-POWER if I have already used a Supporter this turn?
Yes, you are not playing a second Supporter, you are just using the Supporter's effect as the effect of the power.
Source: Undaunted FAQ (2010-09-09), PUI Rules Team (2010-09-09)
When I use Smeargle's "Portrait" Poke-POWER to look at my opponent's hand, can I terminate the power's effect without choosing a Supporter card?
No, you cannot. You must choose a Supporter card when you use the effect if the opponent has one in their hand.
Source: Undaunted FAQ (2010-09-09), PUI Rules Team (2010-09-09)