Can I use Hisuian Typhlosion's "Supernatural Orb" Ability if my opponent's Active Pokemon is already both Burned and Confused?
You may use Supernatural Orb if your opponent's Active Pokemon is either Burned OR Confused (or neither), but not if it is already both Burned AND Confused.
Source: Astral Radiance FAQ; TPCi Rules Team (2022-05-26)

Relevant cards

Note: All applicable cards may not be listed below.
SWSH10_52
SWSH10_52