Can you use Devolution Spray or Golurk's "Devolution Punch" attack against a Mega Pokemon, and if so what happens to the Mega Pokemon?
Mega Pokemon are evolved Pokemon, so the Mega Pokemon card is removed, but the underlying Pokemon and all other cards attached stay in play (unless the Pokemon is KO'd, of course).
Source: XY FAQ (2014-02-06), TPCi Rules Team (2014-02-06)

Relevant cards

Note: All applicable cards may not be listed below.
WOTCB1_72